Consumers Union of Japan has signed the global appeal to stop gene drives:
Gene drive technology uses new genetic engineering techniques including CRISPR/Cas9 to forcibly spread genetically engineered traits, including lethal ones, throughout entire populations and species of organisms. Once released into the environment, gene drive organisms cannot be recalled nor controlled thus preempting and overriding the ability of nations, Indigenous Peoples, local communities and future generations to take their own decisions.
Gene drives work against natural rules of inheritance forcing nearly 100% instead of the usual 50% of offspring to inherit their genetically engineered traits. Whereas existing biosafety systems are designed to limit the spread and persistence of living modified organisms to mitigate against adverse impacts, gene drives are intended to spread genetic modifications to alter species and ecosystems. This would undermine the integrity of the UN Cartagena Protocol and international and national biosafety systems, including the procedures for Advanced Informed Agreement (AIA) of countries and Free, Prior and Informed consent (FPIC) of Indigenous Peoples and local communities.